Welcome! Contact Us
Research in the
Dmochowski lab encompasses
many
areas of Bioinorganic, Bioorganic, and Biophysical Chemistry, as well as Chemical Biology.
Our lab
is comprised of people with backgrounds spanning these disciplines. We
are
developing
small molecules, proteins, and spectroscopic techniques for
studying complex biomolecular systems. Our approach
involves cycles of molecular design, synthesis, and measurement.
 We are synthesizing light-activated oligonucleotides and
Xe-129
MRI contrast agents to elucidate
protein interactions involved in vertebrate development,
limb regeneration, and the progression of many diseases, including
cancer. We are also developing novel nano/biomaterials using
proteins for the synthesis and assembly of
metal nanoparticles.
Useful Links Ivan@UPenn Chemistry UPenn Department of Chemistry American Chemical Society |
Recent
Highlights 2008 September Garry’s work on delivering cryptophanes to cells is accepted by Bioconjugate Chemistry. Aru’s work on synthesizing a water-soluble cryptophane with unprecedented xenon affinity is accepted by J. Am. Chem. Soc. Jenny’s work on developing Xe-129 NMR biosensors for carbonic anhydase is accepted by J. Am. Chem. Soc. August Aru, Joe, XinJing, and Ivan give talks at the Philadelphia ACS meeting. May Crystal structure of Jenny’s Xe biosensor complexed with carbonic anhydrase II is published with the Christianson lab in J. Am. Chem. Soc. January Two new graduate students join the lab. We welcome Brittani Ruble (Bio) and Jasmina Cheung-Lau (Inorganic)! XinJing’s paper showing photomodulation of c-myb expression in K562 cells is published in Nucleic Acids Res. |