Feed aggregator

Roger Tsien 1952–2016

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1269 (2016). doi:10.1038/nn.4410

Author: David Kleinfeld

Life and death rest on a bivalent chromatin state

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1271 (2016). doi:10.1038/nn.4396

Author: X William Yang

Neurons require lifelong maintenance of their transcriptional program, which includes stable expression of cell-type-specific identity genes. A study now shows that PRC2-mediated chromatin repression in adulthood is critical for the maintenance of neuronal identity gene expression and neuronal survival.

Too bored to stay awake

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1274 (2016). doi:10.1038/nn.4383

Authors: Michael Happ & Michael M Halassa

While the relationship between motivation and sleep is intuitive, its behavioral and neural features are poorly understood. A new study tackles both issues, showing that dopaminergic neurons in the ventral tegmental area mediate this relationship.

A useful code for sequences

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1276 (2016). doi:10.1038/nn.4391

Author: Nikolai Axmacher

A neural code for sequences needs to allow the recruitment of plasticity mechanisms that link successive items. New results suggest that this is achieved by coupling gamma band activity to specific phases of theta oscillations.

Dorsal anterior cingulate: a Rorschach test for cognitive neuroscience

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1278 (2016). doi:10.1038/nn.4387

Authors: R Becket Ebitz & Benjamin Yost Hayden

The dorsal anterior cingulate cortex is one of the most beguiling regions of the brain. Understanding its essential function has become a holy grail for many cognitive neuroscientists. With this scrutiny has come contention. In this issue, two teams of neuroscientists with different views argue for their favored interpretation of neural activity in this region. Here, we provide some background and context for this debate.

Value, search, persistence and model updating in anterior cingulate cortex

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1280 (2016). doi:10.1038/nn.4382

Authors: Nils Kolling, Marco K Wittmann, Tim E J Behrens, Erie D Boorman, Rogier B Mars & Matthew F S Rushworth

Dorsal anterior cingulate cortex and the value of control

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1286 (2016). doi:10.1038/nn.4384

Authors: Amitai Shenhav, Jonathan D Cohen & Matthew M Botvinick

Evolving insights into RNA modifications and their functional diversity in the brain

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1292 (2016). doi:10.1038/nn.4378

Authors: Sarah Nainar, Paul R Marshall, Christina R Tyler, Robert C Spitale & Timothy W Bredy

LTD-like molecular pathways in developmental synaptic pruning

Neuroscience in the News - Tue, 09/27/2016 - 12:00am

Nature Neuroscience 19, 1299 (2016). doi:10.1038/nn.4389

Authors: Claire Piochon, Masanobu Kano & Christian Hansel

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Nature Neuroscience - Mon, 09/26/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4399

Authors: Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Thanneer M Perumal, Douglas M Ruderfer, Edwin C Oh, Aaron Topol, Hardik R Shah, Lambertus L Klei, Robin Kramer, Dalila Pinto, Zeynep H Gümüş, A Ercument Cicek, Kristen K Dang, Andrew Browne, Cong Lu, Lu Xie, Ben Readhead, Eli A Stahl, Jianqiu Xiao, Mahsa Parvizi, Tymor Hamamsy, John F Fullard, Ying-Chih Wang, Milind C Mahajan, Jonathan M J Derry, Joel T Dudley, Scott E Hemby, Benjamin A Logsdon, Konrad Talbot, Towfique Raj, David A Bennett, Philip L De Jager, Jun Zhu, Bin Zhang, Patrick F Sullivan, Andrew Chess, Shaun M Purcell, Leslie A Shinobu, Lara M Mangravite, Hiroyoshi Toyoshiba, Raquel E Gur, Chang-Gyu Hahn, David A Lewis, Vahram Haroutunian, Mette A Peters, Barbara K Lipska, Joseph D Buxbaum, Eric E Schadt, Keisuke Hirai, Kathryn Roeder, Kristen J Brennand, Nicholas Katsanis, Enrico Domenici, Bernie Devlin & Pamela Sklar

MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors

Nature Neuroscience - Mon, 09/26/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4395

Authors: Melissa Mahgoub, Megumi Adachi, Kanzo Suzuki, Xihui Liu, Ege T Kavalali, Maria H Chahrour & Lisa M Monteggia

Neural substrate of dynamic Bayesian inference in the cerebral cortex

Nature Neuroscience - Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4390

Authors: Akihiro Funamizu, Bernd Kuhn & Kenji Doya

Dynamic GABAergic afferent modulation of AgRP neurons

Nature Neuroscience - Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4392

Authors: Alastair S Garfield, Bhavik P Shah, Christian R Burgess, Monica M Li, Chia Li, Jennifer S Steger, Joseph C Madara, John N Campbell, Daniel Kroeger, Thomas E Scammell, Bakhos A Tannous, Martin G Myers, Mark L Andermann, Michael J Krashes & Bradford B Lowell

Mechanosensing is critical for axon growth in the developing brain

Nature Neuroscience - Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4394

Authors: David E Koser, Amelia J Thompson, Sarah K Foster, Asha Dwivedy, Eva K Pillai, Graham K Sheridan, Hanno Svoboda, Matheus Viana, Luciano da F Costa, Jochen Guck, Christine E Holt & Kristian Franze

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

Nature Neuroscience - Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4393

Authors: Karla L Miller, Fidel Alfaro-Almagro, Neal K Bangerter, David L Thomas, Essa Yacoub, Junqian Xu, Andreas J Bartsch, Saad Jbabdi, Stamatios N Sotiropoulos, Jesper L R Andersson, Ludovica Griffanti, Gwenaëlle Douaud, Thomas W Okell, Peter Weale, Iulius Dragonu, Steve Garratt, Sarah Hudson, Rory Collins, Mark Jenkinson, Paul M Matthews & Stephen M Smith

L1-associated genomic regions are deleted in somatic cells of the healthy human brain

Nature Neuroscience - Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4388

Authors: Jennifer A Erwin, Apuã C M Paquola, Tatjana Singer, Iryna Gallina, Mark Novotny, Carolina Quayle, Tracy A Bedrosian, Francisco I A Alves, Cheyenne R Butcher, Joseph R Herdy, Anindita Sarkar, Roger S Lasken, Alysson R Muotri & Fred H Gage

Experience-dependent spatial expectations in mouse visual cortex

Nature Neuroscience - Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4385

Authors: Aris Fiser, David Mahringer, Hassana K Oyibo, Anders V Petersen, Marcus Leinweber & Georg B Keller

Global dynamics of selective attention and its lapses in primary auditory cortex

Nature Neuroscience - Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4386

Authors: Peter Lakatos, Annamaria Barczak, Samuel A Neymotin, Tammy McGinnis, Deborah Ross, Daniel C Javitt & Monica Noelle O'Connell

The opposite lane: a path to memories?

Neuroscience in the News - Mon, 09/05/2016 - 12:00am

Nature Neuroscience 19, 1273 (2016). doi:10.1038/nn.4381

Author: Bo Li

Sound information travels from auditory cortex to lateral amygdala, but a newly identified pathway runs in the opposite direction. It undergoes plasticity and is required for memory recall during auditory fear conditioning.

Selective synaptic remodeling of amygdalocortical connections associated with fear memory

Neuroscience in the News - Mon, 09/05/2016 - 12:00am

Nature Neuroscience 19, 1348 (2016). doi:10.1038/nn.4370

Authors: Yang Yang, Dan-qian Liu, Wei Huang, Juan Deng, Yangang Sun, Yi Zuo & Mu-ming Poo

Syndicate content