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Light-regulated translational control of circadian behavior by eIF4E phosphorylation

Nature Neuroscience - Mon, 04/27/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4010

Authors: Ruifeng Cao, Christos G Gkogkas, Nuria de Zavalia, Ian D Blum, Akiko Yanagiya, Yoshinori Tsukumo, Haiyan Xu, Choogon Lee, Kai-Florian Storch, Andrew C Liu, Shimon Amir & Nahum Sonenberg

An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity

Nature Neuroscience - Mon, 04/27/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4002

Authors: Naiyan Chen, Hiroki Sugihara & Mriganka Sur

A neural basis for melanocortin-4 receptor–regulated appetite

Nature Neuroscience - Mon, 04/27/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4011

Authors: Alastair S Garfield, Chia Li, Joseph C Madara, Bhavik P Shah, Emily Webber, Jennifer S Steger, John N Campbell, Oksana Gavrilova, Charlotte E Lee, David P Olson, Joel K Elmquist, Bakhos A Tannous, Michael J Krashes & Bradford B Lowell

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease

Nature Neuroscience - Mon, 04/27/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4004

Authors: Ariadna Laguna, Nicoletta Schintu, André Nobre, Alexandra Alvarsson, Nikolaos Volakakis, Jesper Kjaer Jacobsen, Marta Gómez-Galán, Elena Sopova, Eliza Joodmardi, Takashi Yoshitake, Qiaolin Deng, Jan Kehr, Johan Ericson, Per Svenningsson, Oleg Shupliakov & Thomas Perlmann

Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

Nature Neuroscience - Mon, 04/27/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4008

Authors: Huimei Yu, Yijing Su, Jaehoon Shin, Chun Zhong, Junjie U Guo, Yi-Lan Weng, Fuying Gao, Daniel H Geschwind, Giovanni Coppola, Guo-li Ming & Hongjun Song

Ca2+ signaling in astrocytes from Ip3r2−/− mice in brain slices and during startle responses in vivo

Nature Neuroscience - Mon, 04/20/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4001

Authors: Rahul Srinivasan, Ben S Huang, Sharmila Venugopal, April D Johnston, Hua Chai, Hongkui Zeng, Peyman Golshani & Baljit S Khakh

Neural encoding of opposing strategy values in anterior and posterior cingulate cortex

Nature Neuroscience - Mon, 04/20/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3999

Authors: Xiaohong Wan, Kang Cheng & Keiji Tanaka

A coding-independent function of an alternative Ube3a transcript during neuronal development

Nature Neuroscience - Mon, 04/13/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3996

Authors: Jeremy Valluy, Silvia Bicker, Ayla Aksoy-Aksel, Martin Lackinger, Simon Sumer, Roberto Fiore, Tatjana Wüst, Dominik Seffer, Franziska Metge, Christoph Dieterich, Markus Wöhr, Rainer Schwarting & Gerhard Schratt

Mesopontine median raphe regulates hippocampal ripple oscillation and memory consolidation

Nature Neuroscience - Mon, 04/13/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3998

Authors: Dong V Wang, Hau-Jie Yau, Carl J Broker, Jen-Hui Tsou, Antonello Bonci & Satoshi Ikemoto

Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease

Nature Neuroscience - Mon, 04/13/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3997

Authors: Coralie de Hemptinne, Nicole C Swann, Jill L Ostrem, Elena S Ryapolova-Webb, Marta San Luciano, Nicholas B Galifianakis & Philip A Starr

Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo

Nature Neuroscience - Mon, 04/06/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3991

Authors: Sigrid Mensch, Marion Baraban, Rafael Almeida, Tim Czopka, Jessica Ausborn, Abdeljabbar El Manira & David A Lyons

The myelination of axons by oligodendrocytes markedly affects CNS function, but how this is regulated by neuronal activity in vivo is not known. We found that blocking synaptic vesicle release impaired CNS myelination by reducing the number of myelin sheaths made by individual oligodendrocytes during their short period of formation. We also found that stimulating neuronal activity increased myelin sheath formation by individual oligodendrocytes. These data indicate that neuronal activity regulates the myelinating capacity of single oligodendrocytes.

Learning-induced autonomy of sensorimotor systems

Nature Neuroscience - Mon, 04/06/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3993

Authors: Danielle S Bassett, Muzhi Yang, Nicholas F Wymbs & Scott T Grafton

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

Nature Neuroscience - Mon, 04/06/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3995

Authors: Christopher L Frank, Fang Liu, Ranjula Wijayatunge, Lingyun Song, Matthew T Biegler, Marty G Yang, Christopher M Vockley, Alexias Safi, Charles A Gersbach, Gregory E Crawford & Anne E West

Neuronal activity biases axon selection for myelination in vivo

Nature Neuroscience - Mon, 04/06/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3992

Authors: Jacob H Hines, Andrew M Ravanelli, Rani Schwindt, Ethan K Scott & Bruce Appel

Medial prefrontal cortical activity reflects dynamic re-evaluation during voluntary persistence

Nature Neuroscience - Mon, 04/06/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3994

Authors: Joseph T McGuire & Joseph W Kable

Synaptic diversity enables temporal coding of coincident multisensory inputs in single neurons

Nature Neuroscience - Mon, 03/30/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3974

Authors: François P Chabrol, Alexander Arenz, Martin T Wiechert, Troy W Margrie & David A DiGregorio

Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

Nature Neuroscience - Mon, 03/30/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3989

Authors: Shohei Furutachi, Hiroaki Miya, Tomoyuki Watanabe, Hiroki Kawai, Norihiko Yamasaki, Yujin Harada, Itaru Imayoshi, Mark Nelson, Keiichi I Nakayama, Yusuke Hirabayashi & Yukiko Gotoh

Family income, parental education and brain structure in children and adolescents

Nature Neuroscience - Mon, 03/30/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3983

Authors: Kimberly G Noble, Suzanne M Houston, Natalie H Brito, Hauke Bartsch, Eric Kan, Joshua M Kuperman, Natacha Akshoomoff, David G Amaral, Cinnamon S Bloss, Ondrej Libiger, Nicholas J Schork, Sarah S Murray, B J Casey, Linda Chang, Thomas M Ernst, Jean A Frazier, Jeffrey R Gruen, David N Kennedy, Peter Van Zijl, Stewart Mostofsky, Walter E Kaufmann, Tal Kenet, Anders M Dale, Terry L Jernigan & Elizabeth R Sowell

Brain feminization requires active repression of masculinization via DNA methylation

Nature Neuroscience - Mon, 03/30/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3988

Authors: Bridget M Nugent, Christopher L Wright, Amol C Shetty, Georgia E Hodes, Kathryn M Lenz, Anup Mahurkar, Scott J Russo, Scott E Devine & Margaret M McCarthy

Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity

Nature Neuroscience - Mon, 03/30/2015 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3984

Authors: Daisuke Tsuboi, Keisuke Kuroda, Motoki Tanaka, Takashi Namba, Yukihiko Iizuka, Shinichiro Taya, Tomoyasu Shinoda, Takao Hikita, Shinsuke Muraoka, Michiro Iizuka, Ai Nimura, Akira Mizoguchi, Nobuyuki Shiina, Masahiro Sokabe, Hideyuki Okano, Katsuhiko Mikoshiba & Kozo Kaibuchi

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