Feed aggregator

The mythical brain

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1137 (2014). doi:10.1038/nn.3802

It is not enough to refute common myths about the brain: scientists need to highlight interesting real science as well.

The epigenetic landscape of Alzheimer's disease

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1138 (2014). doi:10.1038/nn.3792

Authors: Jenny Lord & Carlos Cruchaga

Two independent epigenome-wide association studies of Alzheimer's disease cohorts have identified overlapping methylation signals in four loci, ANK1, RPL13, RHBDF2 and CDH23, not previously associated with Alzheimer's disease. These studies also suggest that epigenetic changes contribute more to Alzheimer's disease than expected.

CLEARance wars: PolyQ strikes back

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1140 (2014). doi:10.1038/nn.3793

Authors: X William Yang & Ai Yamamoto

Polyglutamine expansion in the androgen receptor, causing X-linked spinal and bulbar muscular atrophy, impairs its function as a transcriptional coactivator regulating an extensive network of proteins involved in protein clearance.

All that glitters is not reward signal

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1142 (2014). doi:10.1038/nn.3795

Authors: Benjamin Y Hayden & Sarah R Heilbronner

In this issue, Shenhav et al. critically evaluate the idea that neural correlates of value actually represent value. They describe how, in many situations, value correlates can reflect other cognitive factors, such as decisional difficulty.

Scenting Waldo: analyzing olfactory scenes

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1144 (2014). doi:10.1038/nn.3796

Author: Timothy E Holy

Olfaction has often been described as a 'synthetic' sense. A study now reveals a surprising capacity to resolve individual odorants in complex mixtures, with implications for how the nervous system recognizes objects.

Reward processing by the lateral habenula in normal and depressive behaviors

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1146 (2014). doi:10.1038/nn.3779

Authors: Christophe D Proulx, Okihide Hikosaka & Roberto Malinow

Corrigendum: Immune surveillance in the central nervous system

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1286 (2014). doi:10.1038/nn0914-1286a

Author: Shalina S Ousman & Paul Kubes

Addendum: Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1286 (2014). doi:10.1038/nn0914-1286b

Author: Martijn Figee, Judy Luigjes, Ruud Smolders, Carlos-Eduardo Valencia-Alfonso, Guido van Wingen, Bart de Kwaasteniet, Mariska Mantione, Pieter Ooms, Pelle de Koning, Nienke Vulink, Nina Levar, Lukas Droge, Pepijn van den Munckhof, P Richard Schuurman, Aart Nederveen, Wim van den Brink, Ali Mazaheri, Matthijs Vink & Damiaan Denys

Corrigendum: EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1286 (2014). doi:10.1038/nn0914-1286c

Author: Jiali Li, Ronald P Hart, Elyse M Mallimo, Mavis R Swerdel, Alexander W Kusnecov & Karl Herrup

Corrigendum: Identification of a unique TGF-β–dependent molecular and functional signature in microglia

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1286 (2014). doi:10.1038/nn0914-1286d

Author: Oleg Butovsky, Mark P Jedrychowski, Craig S Moore, Ron Cialic, Amanda J Lanser, Galina Gabriely, Thomas Koeglsperger, Ben Dake, Pauline M Wu, Camille E Doykan, Zain Fanek, LiPing Liu, Zhuoxun Chen, Jeffrey D Rothstein, Richard M Ransohoff, Steven P Gygi, Jack P Antel & Howard L Weiner

Corrigendum: Post-study caffeine administration enhances memory consolidation in humans

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1287 (2014). doi:10.1038/nn0914-1287a

Author: Daniel Borota, Elizabeth Murray, Gizem Keceli, Allen Chang, Joseph M Watabe, Maria Ly, John P Toscano & Michael A Yassa

Corrigendum: LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1287 (2014). doi:10.1038/nn0914-1287b

Author: Loukia Parisiadou, Jia Yu, Carmelo Sgobio, Chengsong Xie, Guoxiang Liu, Lixin Sun, Xing-Long Gu, Xian Lin, Nicole A Crowley, David M Lovinger & Huaibin Cai

Corrigendum: LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1287 (2014). doi:10.1038/nn0914-1287c

Author: Loukia Parisiadou, Jia Yu, Carmelo Sgobio, Chengsong Xie, Guoxiang Liu, Lixin Sun, Xing-Long Gu, Xian Lin, Nicole A Crowley, David M Lovinger & Huaibin Cai

Erratum: Peripheral gating of pain signals by endogenous lipid mediators

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1287 (2014). doi:10.1038/nn0914-1287d

Author: Daniele Piomelli & Oscar Sasso

Erratum: Orbitofrontal activation restores insight lost after cocaine use

Neuroscience in the News - Tue, 08/26/2014 - 12:00am

Nature Neuroscience 17, 1287 (2014). doi:10.1038/nn0914-1287e

Author: Federica Lucantonio, Yuji K Takahashi, Alexander F Hoffman, Chun Chang, Sheena Bali-Chaudhary, Yavin Shaham, Carl R Lupica & Geoffrey Schoenbaum

Dimensionality reduction for large-scale neural recordings

Nature Neuroscience - Sun, 08/24/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3776

Authors: John P Cunningham & Byron M Yu

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

Nature Neuroscience - Sun, 08/24/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3790

Authors: Stacey M Glasgow, Wenyi Zhu, C Claus Stolt, Teng-Wei Huang, Fuyi Chen, Joseph J LoTurco, Jeffrey L Neul, Michael Wegner, Carrie Mohila & Benjamin Deneen

Image familiarization sharpens response dynamics of neurons in inferotemporal cortex

Nature Neuroscience - Sun, 08/24/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3794

Authors: Travis Meyer, Christopher Walker, Raymond Y Cho & Carl R Olson

Activity-dependent regulation of astrocyte GAT levels during synaptogenesis

Nature Neuroscience - Sun, 08/24/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3791

Authors: Allie K Muthukumar, Tobias Stork & Marc R Freeman

Gamma-range synchronization of fast-spiking interneurons can enhance detection of tactile stimuli

Nature Neuroscience - Sun, 08/24/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3797

Authors: Joshua H Siegle, Dominique L Pritchett & Christopher I Moore

Syndicate content