Nature Neuroscience

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Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal reflects the entire spectrum of neuroscience, from molecular to cognitive.
Updated: 8 hours 54 min ago

Dopamine neurons share common response function for reward prediction error

Mon, 02/08/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4239

Authors: Neir Eshel, Ju Tian, Michael Bukwich & Naoshige Uchida

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

Mon, 02/08/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4236

Authors: Nicholas L Weilinger, Alexander W Lohman, Brooke D Rakai, Evelyn M M Ma, Jennifer Bialecki, Valentyna Maslieieva, Travis Rilea, Mischa V Bandet, Nathan T Ikuta, Lucas Scott, Michael A Colicos, G Campbell Teskey, Ian R Winship & Roger J Thompson

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Mon, 02/01/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4228

Authors: Barbara Franke, Jason L Stein, Stephan Ripke, Verneri Anttila, Derrek P Hibar, Kimm J E van Hulzen, Alejandro Arias-Vasquez, Jordan W Smoller, Thomas E Nichols, Michael C Neale, Andrew M McIntosh, Phil Lee, Francis J McMahon, Andreas Meyer-Lindenberg, Manuel Mattheisen, Ole A Andreassen, Oliver Gruber, Perminder S Sachdev, Roberto Roiz-Santiañez, Andrew J Saykin, Stefan Ehrlich, Karen A Mather, Jessica A Turner, Emanuel Schwarz, Anbupalam Thalamuthu, Yin Yao, Yvonne Y W Ho, Nicholas G Martin, Margaret J Wright, Michael C O'Donovan, Paul M Thompson, Benjamin M Neale, Sarah E Medland & Patrick F Sullivan

Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR

Mon, 02/01/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4235

Authors: Derek J C Tai, Ashok Ragavendran, Poornima Manavalan, Alexei Stortchevoi, Catarina M Seabra, Serkan Erdin, Ryan L Collins, Ian Blumenthal, Xiaoli Chen, Yiping Shen, Mustafa Sahin, Chengsheng Zhang, Charles Lee, James F Gusella & Michael E Talkowski

PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation

Mon, 01/25/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4231

Authors: Smitha Karunakaran, Ananya Chowdhury, Flavio Donato, Charles Quairiaux, Christoph M Michel & Pico Caroni

Separate circuitries encode the hedonic and nutritional values of sugar

Mon, 01/25/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4224

Authors: Luis A Tellez, Wenfei Han, Xiaobing Zhang, Tatiana L Ferreira, Isaac O Perez, Sara J Shammah-Lagnado, Anthony N van den Pol & Ivan E de Araujo

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

Mon, 01/25/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4229

Authors: Marit W Vermunt, Sander C Tan, Bas Castelijns, Geert Geeven, Peter Reinink, Ewart de Bruijn, Ivanela Kondova, Stephan Persengiev, Ronald Bontrop, Edwin Cuppen, Wouter de Laat & Menno P Creyghton

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

Mon, 01/18/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4225

Authors: Shira Knafo, Cristina Sánchez-Puelles, Ernest Palomer, Igotz Delgado, Jonathan E Draffin, Janire Mingo, Tina Wahle, Kanwardeep Kaleka, Liping Mou, Inmaculada Pereda-Perez, Edvin Klosi, Erik B Faber, Heidi M Chapman, Laura Lozano-Montes, Ana Ortega-Molina, Lara Ordóñez-Gutiérrez, Francisco Wandosell, Jose Viña, Carlos G Dotti, Randy A Hall, Rafael Pulido, Nashaat Z Gerges, Andrew M Chan, Mark R Spaller, Manuel Serrano, César Venero & José A Esteban

Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking

Mon, 01/18/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4223

Authors: Jérémie Naudé, Stefania Tolu, Malou Dongelmans, Nicolas Torquet, Sébastien Valverde, Guillaume Rodriguez, Stéphanie Pons, Uwe Maskos, Alexandre Mourot, Fabio Marti & Philippe Faure

On-going computation of whisking phase by mechanoreceptors

Mon, 01/18/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4221

Authors: Avner Wallach, Knarik Bagdasarian & Ehud Ahissar

Illuminating next-generation brain therapies

Mon, 01/18/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4232

Authors: Emily Ferenczi & Karl Deisseroth

A clinical trial inspired and guided by optogenetics experiments in rodents reports the outcome of targeted transcranial magnetic stimulation in patients suffering from cocaine addiction.

Microglial brain region−dependent diversity and selective regional sensitivities to aging

Mon, 01/18/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4222

Authors: Kathleen Grabert, Tom Michoel, Michail H Karavolos, Sara Clohisey, J Kenneth Baillie, Mark P Stevens, Tom C Freeman, Kim M Summers & Barry W McColl

KIF1A inhibition immortalizes brain stem cells but blocks BDNF-mediated neuronal migration

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4213

Authors: Aurelie Carabalona, Daniel Jun-Kit Hu & Richard B Vallee

Parallel specification of competing sensorimotor control policies for alternative action options

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4214

Authors: Jason P Gallivan, Lindsey Logan, Daniel M Wolpert & J Randall Flanagan

Bidirectional GABAergic control of action potential firing in newborn hippocampal granule cells

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4218

Authors: Stefanie Heigele, Sébastien Sultan, Nicolas Toni & Josef Bischofberger

Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4219

Authors: Vikrant Kapoor, Allison C Provost, Prateek Agarwal & Venkatesh N Murthy

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4211

Authors: Qiang Liu, Nader Sanai, Wei-Na Jin, Antonio La Cava, Luc Van Kaer & Fu-Dong Shi

Coherent neuronal ensembles are rapidly recruited when making a look-reach decision

Mon, 01/11/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4210

Authors: Yan T Wong, Margaret M Fabiszak, Yevgeny Novikov, Nathaniel D Daw & Bijan Pesaran

Laterodorsal tegmentum interneuron subtypes oppositely regulate olfactory cue-induced innate fear

Mon, 01/04/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4208

Authors: Hongbin Yang, Junhua Yang, Wang Xi, Sijia Hao, Benyan Luo, Xiaobin He, Liya Zhu, Huifang Lou, Yan-qin Yu, Fuqiang Xu, Shumin Duan & Hao Wang

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

Mon, 01/04/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4216

Authors: Bosiljka Tasic, Vilas Menon, Thuc Nghi Nguyen, Tae Kyung Kim, Tim Jarsky, Zizhen Yao, Boaz Levi, Lucas T Gray, Staci A Sorensen, Tim Dolbeare, Darren Bertagnolli, Jeff Goldy, Nadiya Shapovalova, Sheana Parry, Changkyu Lee, Kimberly Smith, Amy Bernard, Linda Madisen, Susan M Sunkin, Michael Hawrylycz, Christof Koch & Hongkui Zeng