Nature Neuroscience

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Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal reflects the entire spectrum of neuroscience, from molecular to cognitive.
Updated: 3 hours 13 min ago

Hierarchical competitions subserving multi-attribute choice

Sun, 10/12/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3836

Authors: Laurence T Hunt, Raymond J Dolan & Timothy E J Behrens

Attention can either increase or decrease spike count correlations in visual cortex

Sun, 10/12/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3835

Authors: Douglas A Ruff & Marlene R Cohen

Cortical neurogenesis in the absence of centrioles

Sun, 10/05/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3831

Authors: Ryan Insolera, Hisham Bazzi, Wei Shao, Kathryn V Anderson & Song-Hai Shi

Anchoring the neural compass: coding of local spatial reference frames in human medial parietal lobe

Sun, 10/05/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3834

Authors: Steven A Marchette, Lindsay K Vass, Jack Ryan & Russell A Epstein

Representation of aversive prediction errors in the human periaqueductal gray

Sun, 10/05/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3832

Authors: Mathieu Roy, Daphna Shohamy, Nathaniel Daw, Marieke Jepma, G Elliott Wimmer & Tor D Wager

Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division

Sun, 09/28/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3815

Authors: Robert A Hill, Kiran D Patel, Christopher M Goncalves, Jaime Grutzendler & Akiko Nishiyama

Neural correlates of water reward in thirsty Drosophila

Sun, 09/28/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3827

Authors: Suewei Lin, David Owald, Vikram Chandra, Clifford Talbot, Wolf Huetteroth & Scott Waddell

A somatosensory circuit for cooling perception in mice

Sun, 09/28/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3828

Authors: Nevena Milenkovic, Wen-Jie Zhao, Jan Walcher, Tobias Albert, Jan Siemens, Gary R Lewin & James F A Poulet

Neural antecedents of self-initiated actions in secondary motor cortex

Sun, 09/28/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3826

Authors: Masayoshi Murakami, M Inês Vicente, Gil M Costa & Zachary F Mainen

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

Sun, 09/21/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3822

Authors: Andrei I Molosh, Philip L Johnson, John P Spence, David Arendt, Lauren M Federici, Cristian Bernabe, Steven P Janasik, Zaneer M Segu, Rajesh Khanna, Chirayu Goswami, Weiguo Zhu, Su-Jung Park, Lang Li, Yehia S Mechref, D Wade Clapp & Anantha Shekhar

Tactile frequency discrimination is enhanced by circumventing neocortical adaptation

Sun, 09/21/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3821

Authors: Simon Musall, Wolfger von der Behrens, Johannes M Mayrhofer, Bruno Weber, Fritjof Helmchen & Florent Haiss

Single rodent mesohabenular axons release glutamate and GABA

Sun, 09/21/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3823

Authors: David H Root, Carlos A Mejias-Aponte, Shiliang Zhang, Hui-Ling Wang, Alexander F Hoffman, Carl R Lupica & Marisela Morales

Visualizing an emotional valence map in the limbic forebrain by TAI-FISH

Sun, 09/21/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3813

Authors: Jianbo Xiu, Qi Zhang, Tao Zhou, Ting-ting Zhou, Yang Chen & Hailan Hu

Neural compensation in older people with brain amyloid-β deposition

Sun, 09/14/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3806

Authors: Jeremy A Elman, Hwamee Oh, Cindee M Madison, Suzanne L Baker, Jacob W Vogel, Shawn M Marks, Sam Crowley, James P O'Neil & William J Jagust

Recruitment of extra neural resources may allow people to maintain normal cognition despite amyloid-β (Aβ) plaques. Previous fMRI studies have reported such hyperactivation, but it is unclear whether increases represent compensation or aberrant overexcitation. We found that older adults with Aβ deposition had reduced deactivations in task-negative regions, but increased activation in task-positive regions related to more detailed memory encoding. The association between higher activity and more detailed memories suggests that Aβ-related hyperactivation is compensatory.

Metabolic regulator LKB1 is crucial for Schwann cell–mediated axon maintenance

Sun, 09/07/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3809

Authors: Bogdan Beirowski, Elisabetta Babetto, Judith P Golden, Ying-Jr Chen, Kui Yang, Richard W Gross, Gary J Patti & Jeffrey Milbrandt

Genome-wide identification and characterization of functional neuronal activity–dependent enhancers

Sun, 09/07/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3808

Authors: Athar N Malik, Thomas Vierbuchen, Martin Hemberg, Alex A Rubin, Emi Ling, Cameron H Couch, Hume Stroud, Ivo Spiegel, Kyle Kai-How Farh, David A Harmin & Michael E Greenberg

Information-limiting correlations

Sun, 09/07/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3807

Authors: Rubén Moreno-Bote, Jeffrey Beck, Ingmar Kanitscheider, Xaq Pitkow, Peter Latham & Alexandre Pouget

Perceptual training continuously refines neuronal population codes in primary visual cortex

Sun, 09/07/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3805

Authors: Yin Yan, Malte J Rasch, Minggui Chen, Xiaoping Xiang, Min Huang, Si Wu & Wu Li

Damage to dorsolateral prefrontal cortex affects tradeoffs between honesty and self-interest

Sun, 08/31/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3798

Authors: Lusha Zhu, Adrianna C Jenkins, Eric Set, Donatella Scabini, Robert T Knight, Pearl H Chiu, Brooks King-Casas & Ming Hsu

Substantial correlational evidence suggests that prefrontal regions are critical to honest and dishonest behavior, but causal evidence specifying the nature of this involvement remains absent. We found that lesions of the human dorsolateral prefrontal cortex (DLPFC) decreased the effect of honesty concerns on behavior in economic games that pit honesty motives against self-interest, but did not affect decisions when honesty concerns were absent. These results point to a causal role for DLPFC in honest behavior.

Reversal of theta rhythm flow through intact hippocampal circuits

Sun, 08/31/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3803

Authors: Jesse Jackson, Bénédicte Amilhon, Romain Goutagny, Jean-Bastien Bott, Frédéric Manseau, Christian Kortleven, Steven L Bressler & Sylvain Williams