Nature Neuroscience

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Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal reflects the entire spectrum of neuroscience, from molecular to cognitive.
Updated: 9 hours 48 min ago

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Mon, 09/26/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4399

Authors: Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Thanneer M Perumal, Douglas M Ruderfer, Edwin C Oh, Aaron Topol, Hardik R Shah, Lambertus L Klei, Robin Kramer, Dalila Pinto, Zeynep H Gümüş, A Ercument Cicek, Kristen K Dang, Andrew Browne, Cong Lu, Lu Xie, Ben Readhead, Eli A Stahl, Jianqiu Xiao, Mahsa Parvizi, Tymor Hamamsy, John F Fullard, Ying-Chih Wang, Milind C Mahajan, Jonathan M J Derry, Joel T Dudley, Scott E Hemby, Benjamin A Logsdon, Konrad Talbot, Towfique Raj, David A Bennett, Philip L De Jager, Jun Zhu, Bin Zhang, Patrick F Sullivan, Andrew Chess, Shaun M Purcell, Leslie A Shinobu, Lara M Mangravite, Hiroyoshi Toyoshiba, Raquel E Gur, Chang-Gyu Hahn, David A Lewis, Vahram Haroutunian, Mette A Peters, Barbara K Lipska, Joseph D Buxbaum, Eric E Schadt, Keisuke Hirai, Kathryn Roeder, Kristen J Brennand, Nicholas Katsanis, Enrico Domenici, Bernie Devlin & Pamela Sklar

MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors

Mon, 09/26/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4395

Authors: Melissa Mahgoub, Megumi Adachi, Kanzo Suzuki, Xihui Liu, Ege T Kavalali, Maria H Chahrour & Lisa M Monteggia

Neural substrate of dynamic Bayesian inference in the cerebral cortex

Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4390

Authors: Akihiro Funamizu, Bernd Kuhn & Kenji Doya

Dynamic GABAergic afferent modulation of AgRP neurons

Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4392

Authors: Alastair S Garfield, Bhavik P Shah, Christian R Burgess, Monica M Li, Chia Li, Jennifer S Steger, Joseph C Madara, John N Campbell, Daniel Kroeger, Thomas E Scammell, Bakhos A Tannous, Martin G Myers, Mark L Andermann, Michael J Krashes & Bradford B Lowell

Mechanosensing is critical for axon growth in the developing brain

Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4394

Authors: David E Koser, Amelia J Thompson, Sarah K Foster, Asha Dwivedy, Eva K Pillai, Graham K Sheridan, Hanno Svoboda, Matheus Viana, Luciano da F Costa, Jochen Guck, Christine E Holt & Kristian Franze

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

Mon, 09/19/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4393

Authors: Karla L Miller, Fidel Alfaro-Almagro, Neal K Bangerter, David L Thomas, Essa Yacoub, Junqian Xu, Andreas J Bartsch, Saad Jbabdi, Stamatios N Sotiropoulos, Jesper L R Andersson, Ludovica Griffanti, Gwenaëlle Douaud, Thomas W Okell, Peter Weale, Iulius Dragonu, Steve Garratt, Sarah Hudson, Rory Collins, Mark Jenkinson, Paul M Matthews & Stephen M Smith

L1-associated genomic regions are deleted in somatic cells of the healthy human brain

Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4388

Authors: Jennifer A Erwin, Apuã C M Paquola, Tatjana Singer, Iryna Gallina, Mark Novotny, Carolina Quayle, Tracy A Bedrosian, Francisco I A Alves, Cheyenne R Butcher, Joseph R Herdy, Anindita Sarkar, Roger S Lasken, Alysson R Muotri & Fred H Gage

Experience-dependent spatial expectations in mouse visual cortex

Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4385

Authors: Aris Fiser, David Mahringer, Hassana K Oyibo, Anders V Petersen, Marcus Leinweber & Georg B Keller

Global dynamics of selective attention and its lapses in primary auditory cortex

Mon, 09/12/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4386

Authors: Peter Lakatos, Annamaria Barczak, Samuel A Neymotin, Tammy McGinnis, Deborah Ross, Daniel C Javitt & Monica Noelle O'Connell

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

Mon, 09/05/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4380

Authors: Yi-Chuan Chen, Hsiao-Ying Kuo, Ulrich Bornschein, Hiroshi Takahashi, Shih-Yun Chen, Kuan-Ming Lu, Hao-Yu Yang, Gui-May Chen, Jing-Ruei Lin, Yi-Hsin Lee, Yun-Chia Chou, Sin-Jhong Cheng, Cheng-Ting Chien, Wolfgang Enard, Wulf Hevers, Svante Pääbo, Ann M Graybiel & Fu-Chin Liu

VTA dopaminergic neurons regulate ethologically relevant sleep–wake behaviors

Mon, 09/05/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4377

Authors: Ada Eban-Rothschild, Gideon Rothschild, William J Giardino, Jeff R Jones & Luis de Lecea

Selective synaptic remodeling of amygdalocortical connections associated with fear memory

Mon, 09/05/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4370

Authors: Yang Yang, Dan-qian Liu, Wei Huang, Juan Deng, Yangang Sun, Yi Zuo & Mu-ming Poo

The opposite lane: a path to memories?

Mon, 09/05/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4381

Author: Bo Li

Sound information travels from auditory cortex to lateral amygdala, but a newly identified pathway runs in the opposite direction. It undergoes plasticity and is required for memory recall during auditory fear conditioning.

Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control

Mon, 08/29/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4376

Authors: Alessandro Furlan, Gioele La Manno, Moritz Lübke, Martin Häring, Hind Abdo, Hannah Hochgerner, Jussi Kupari, Dmitry Usoskin, Matti S Airaksinen, Guillermo Oliver, Sten Linnarsson & Patrik Ernfors

Episodic sequence memory is supported by a theta–gamma phase code

Mon, 08/29/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4374

Authors: Andrew C Heusser, David Poeppel, Youssef Ezzyat & Lila Davachi

Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder

Mon, 08/29/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4373

Authors: Ye E Wu, Neelroop N Parikshak, T Grant Belgard & Daniel H Geschwind

Hypothalamic arcuate nucleus tyrosine hydroxylase neurons play orexigenic role in energy homeostasis

Mon, 08/22/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4372

Authors: Xiaobing Zhang & Anthony N van den Pol

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling

Mon, 08/15/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4364

Authors: Mathias A Böhme, Christina Beis, Suneel Reddy-Alla, Eric Reynolds, Malou M Mampell, Andreas T Grasskamp, Janine Lützkendorf, Dominique Dufour Bergeron, Jan H Driller, Husam Babikir, Fabian Göttfert, Iain M Robinson, Cahir J O'Kane, Stefan W Hell, Markus C Wahl, Ulrich Stelzl, Bernhard Loll, Alexander M Walter & Stephan J Sigrist

Representation of egomotion in rat's trident and E-row whisker cortices

Mon, 08/15/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4363

Authors: Edith Chorev, Patricia Preston-Ferrer & Michael Brecht

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration

Mon, 08/15/2016 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4360

Authors: Melanie von Schimmelmann, Philip A Feinberg, Josefa M Sullivan, Stacy M Ku, Ana Badimon, Mary Kaye Duff, Zichen Wang, Alexander Lachmann, Scott Dewell, Avi Ma'ayan, Ming-Hu Han, Alexander Tarakhovsky & Anne Schaefer