Nature Neuroscience

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Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal reflects the entire spectrum of neuroscience, from molecular to cognitive.
Updated: 9 hours 19 min ago

Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment

Mon, 04/24/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4553

Authors: Anthony Burgos-Robles, Eyal Y Kimchi, Ehsan M Izadmehr, Mary Jane Porzenheim, William A Ramos-Guasp, Edward H Nieh, Ada C Felix-Ortiz, Praneeth Namburi, Christopher A Leppla, Kara N Presbrey, Kavitha K Anandalingam, Pablo A Pagan-Rivera, Melodi Anahtar, Anna Beyeler & Kay M Tye

Identification of spinal circuits involved in touch-evoked dynamic mechanical pain

Mon, 04/24/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4549

Authors: Longzhen Cheng, Bo Duan, Tianwen Huang, Yan Zhang, Yangyang Chen, Olivier Britz, Lidia Garcia-Campmany, Xiangyu Ren, Linh Vong, Bradford B Lowell, Martyn Goulding, Yun Wang & Qiufu Ma

Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior

Mon, 04/24/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4554

Authors: Tsukasa Kamigaki & Yang Dan

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

Mon, 04/17/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4547

Authors: Tuan Leng Tay, Dominic Mai, Jana Dautzenberg, Francisco Fernández-Klett, Gen Lin, Sagar, Moumita Datta, Anne Drougard, Thomas Stempfl, Alberto Ardura-Fabregat, Ori Staszewski, Anca Margineanu, Anje Sporbert, Lars M Steinmetz, J Andrew Pospisilik, Steffen Jung, Josef Priller, Dominic Grün, Olaf Ronneberger & Marco Prinz

Dynamic hidden states underlying working-memory-guided behavior

Mon, 04/17/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4546

Authors: Michael J Wolff, Janina Jochim, Elkan G Akyürek & Mark G Stokes

Comprehensive transcriptome analysis of neocortical layers in humans, chimpanzees and macaques

Mon, 04/17/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4548

Authors: Zhisong He, Dingding Han, Olga Efimova, Patricia Guijarro, Qianhui Yu, Anna Oleksiak, Shasha Jiang, Konstantin Anokhin, Boris Velichkovsky, Stefan Grünewald & Philipp Khaitovich

Sharp wave ripples during learning stabilize the hippocampal spatial map

Mon, 04/10/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4543

Authors: Lisa Roux, Bo Hu, Ronny Eichler, Eran Stark & György Buzsáki

The neural correlates of dreaming

Mon, 04/10/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4545

Authors: Francesca Siclari, Benjamin Baird, Lampros Perogamvros, Giulio Bernardi, Joshua J LaRocque, Brady Riedner, Melanie Boly, Bradley R Postle & Giulio Tononi

Abnormal wiring of CCK+ basket cells disrupts spatial information coding

Mon, 04/10/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4544

Authors: Isabel del Pino, Jorge R Brotons-Mas, André Marques-Smith, Aline Marighetto, Andreas Frick, Oscar Marín & Beatriz Rico

Dopamine transients are sufficient and necessary for acquisition of model-based associations

Mon, 04/03/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4538

Authors: Melissa J Sharpe, Chun Yun Chang, Melissa A Liu, Hannah M Batchelor, Lauren E Mueller, Joshua L Jones, Yael Niv & Geoffrey Schoenbaum

GLP-1 acts on habenular avoidance circuits to control nicotine intake

Mon, 04/03/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4540

Authors: Luis M Tuesta, Zuxin Chen, Alexander Duncan, Christie D Fowler, Masago Ishikawa, Brian R Lee, Xin-An Liu, Qun Lu, Michael Cameron, Matthew R Hayes, Theodore M Kamenecka, Matthew Pletcher & Paul J Kenny

Activity-induced histone modifications govern Neurexin-1 mRNA splicing and memory preservation

Mon, 03/27/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4536

Authors: Xinlu Ding, Sanxiong Liu, Miaomiao Tian, Wenhao Zhang, Tao Zhu, Dongdong Li, Jiawei Wu, HaiTeng Deng, Yichang Jia, Wei Xie, Hong Xie & Ji-Song Guan

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Mon, 03/27/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4537

Authors: Xiuxing Wang, Kailin Yang, Qi Xie, Qiulian Wu, Stephen C Mack, Yu Shi, Leo J Y Kim, Briana C Prager, William A Flavahan, Xiaojing Liu, Meromit Singer, Christopher G Hubert, Tyler E Miller, Wenchao Zhou, Zhi Huang, Xiaoguang Fang, Aviv Regev, Mario L Suvà, Tae Hyun Hwang, Jason W Locasale, Shideng Bao & Jeremy N Rich

Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning

Mon, 03/20/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4531

Authors: Andrea Giovannucci, Aleksandra Badura, Ben Deverett, Farzaneh Najafi, Talmo D Pereira, Zhenyu Gao, Ilker Ozden, Alexander D Kloth, Eftychios Pnevmatikakis, Liam Paninski, Chris I De Zeeuw, Javier F Medina & Samuel S-H Wang

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

Mon, 03/20/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4533

Authors: Thomas A Longden, Fabrice Dabertrand, Masayo Koide, Albert L Gonzales, Nathan R Tykocki, Joseph E Brayden, David Hill-Eubanks & Mark T Nelson

C1 neurons mediate a stress-induced anti-inflammatory reflex in mice

Mon, 03/13/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4526

Authors: Chikara Abe, Tsuyoshi Inoue, Mabel A Inglis, Kenneth E Viar, Liping Huang, Hong Ye, Diane L Rosin, Ruth L Stornetta, Mark D Okusa & Patrice G Guyenet

Regulatory T cells promote myelin regeneration in the central nervous system

Mon, 03/13/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4528

Authors: Yvonne Dombrowski, Thomas O'Hagan, Marie Dittmer, Rosana Penalva, Sonia R Mayoral, Peter Bankhead, Samara Fleville, George Eleftheriadis, Chao Zhao, Michelle Naughton, Rachel Hassan, Jill Moffat, John Falconer, Amanda Boyd, Peter Hamilton, Ingrid V Allen, Adrien Kissenpfennig, Paul N Moynagh, Emma Evergren, Bernard Perbal, Anna C Williams, Rebecca J Ingram, Jonah R Chan, Robin J M Franklin & Denise C Fitzgerald

Manipulating fear associations via optogenetic modulation of amygdala inputs to prefrontal cortex

Mon, 03/13/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4523

Authors: Oded Klavir, Matthias Prigge, Ayelet Sarel, Rony Paz & Ofer Yizhar

α-Synuclein promotes dilation of the exocytotic fusion pore

Mon, 03/13/2017 - 12:00am

Nature Neuroscience. doi:10.1038/nn.4529

Authors: Todd Logan, Jacob Bendor, Chantal Toupin, Kurt Thorn & Robert H Edwards