Nature Neuroscience

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Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal reflects the entire spectrum of neuroscience, from molecular to cognitive.
Updated: 4 hours 36 min ago

Patterns across multiple memories are identified over time

Sun, 06/01/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3736

Authors: Blake A Richards, Frances Xia, Adam Santoro, Jana Husse, Melanie A Woodin, Sheena A Josselyn & Paul W Frankland

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

Sun, 05/25/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3728

Authors: Nitai C Hait, Laura E Wise, Jeremy C Allegood, Megan O'Brien, Dorit Avni, Thomas M Reeves, Pamela E Knapp, Junyan Lu, Cheng Luo, Michael F Miles, Sheldon Milstien, Aron H Lichtman & Sarah Spiegel

ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis

Sun, 05/25/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3732

Authors: Yingbo He, Hui Zhang, Andrea Yung, Saul A Villeda, Philipp A Jaeger, Oluwatobi Olayiwola, Nina Fainberg & Tony Wyss-Coray

Mechanical coupling maintains the fidelity of NMDA receptor–mediated currents

Sun, 05/25/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3724

Authors: Rashek Kazi, Jian Dai, Cameron Sweeney, Huan-Xiang Zhou & Lonnie P Wollmuth

Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human

Sun, 05/25/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3729

Authors: Michel Kielar, Françoise Phan Dinh Tuy, Sara Bizzotto, Cécile Lebrand, Camino de Juan Romero, Karine Poirier, Renske Oegema, Grazia Maria Mancini, Nadia Bahi-Buisson, Robert Olaso, Anne-Gaëlle Le Moing, Katia Boutourlinsky, Dominique Boucher, Wassila Carpentier, Patrick Berquin, Jean-François Deleuze, Richard Belvindrah, Victor Borrell, Egbert Welker, Jamel Chelly, Alexandre Croquelois & Fiona Francis

Spatiotemporal receptive fields of barrel cortex revealed by reverse correlation of synaptic input

Sun, 05/18/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3720

Authors: Alejandro Ramirez, Eftychios A Pnevmatikakis, Josh Merel, Liam Paninski, Kenneth D Miller & Randy M Bruno

Inhibition of mitochondrial protein import by mutant huntingtin

Sun, 05/18/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3721

Authors: Hiroko Yano, Sergei V Baranov, Oxana V Baranova, Jinho Kim, Yanchun Pan, Svitlana Yablonska, Diane L Carlisle, Robert J Ferrante, Albert H Kim & Robert M Friedlander

Induction of self awareness in dreams through frontal low current stimulation of gamma activity

Sun, 05/11/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3719

Authors: Ursula Voss, Romain Holzmann, Allan Hobson, Walter Paulus, Judith Koppehele-Gossel, Ansgar Klimke & Michael A Nitsche

Recent findings link fronto-temporal gamma electroencephalographic (EEG) activity to conscious awareness in dreams, but a causal relationship has not yet been established. We found that current stimulation in the lower gamma band during REM sleep influences ongoing brain activity and induces self-reflective awareness in dreams. Other stimulation frequencies were not effective, suggesting that higher order consciousness is indeed related to synchronous oscillations around 25 and 40 Hz.

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Sun, 05/11/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3717

Authors: Javier Sanchez-Padilla, Jaime N Guzman, Ema Ilijic, Jyothisri Kondapalli, Daniel J Galtieri, Ben Yang, Simon Schieber, Wolfgang Oertel, David Wokosin, Paul T Schumacker & D James Surmeier

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

Sun, 05/04/2014 - 12:00am

Nature Neuroscience. doi:10.1038/nn.3715

Authors: Sachin Katyal, Youngsoo Lee, Karin C Nitiss, Susanna M Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R Russell, John H J Petrini, John L Nitiss & Peter J McKinnon