Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.
A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell’s energy factory. They report their findings this week in Cell.
It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins.
University of Pennsylvania student Joyce Kim is on a mission to spur intercultural dialogue across campus and halfway around the world in North and South Korea.
The University of Pennsylvania’s Volunteers in Public Service Scholarship Program has awarded five $1,000 supplemental scholarships to local college-bound students who have made a difference in West Philadelphia and beyond.
Bringing clarity to a decades-long debate, a national team of researchers led by experts from the Perelman School of Medicine at the University of Pennsylvania has found that adding clot-busting medications known as thrombolytics to conventional approaches when treating sudden-onset pulmonary embolism patients is associated with 47
A team of researchers led by Penn Medicine anesthesiologists have pinpointed the “top five” most common perioperative procedures that are supported by the least amount of clinical evidence, in an effort to direct providers to make more cost-effective treatment decisions.
When a woman experiences a stressful event early in pregnancy, the risk of her child developing autism spectrum disorders or schizophrenia increases. Yet how maternal stress is transmitted to the brain of the developing fetus, leading to these problems in neurodevelopment, is poorly understood.
In conjunction with the first White House Maker Faire being held today, the University of Pennsylvania signed a joint letter along with more than 150 other institutions, pledging support to foster a “generation of makers.” The letter details the need for young tinkerers, inventors and entrepreneurs to bring life to future innovations.
Early American history is marked by multiple displacements of Native American peoples due to multiple removals from their original Indigenous territories. During the late 19th and early 20th centuries, anthropologists participated in other forms of removal by collecting Indigenous narratives and objects for museums.
For Betty Hsu an idea about how to strengthening one’s vocabulary became a rewarding lesson. While at the University of Pennsylvania’s Wharton School, she created ProfessorWord, an online application that helps to boost vocabulary development.
Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure.
Using powerful, newly developed cell culture and mouse models of sporadic Parkinson’s disease (PD), a team of researchers from the Perelman School of Medicine at the University of Pennsylvania, has demonstrated that immunotherapy with specifically targeted antibodies may block the development and spread of PD pathology in the brain.
WHO: Emily Owens
Associate Professor in the Department of Criminology
The Arthur Ross Gallery at the University of Pennsylvania presents Shared Vision: The Myron A. and Anne Jaffe Portenar Collection. It opens to the public on Saturday, July 19, 2014.
Paul W. Meyer, the F. Otto Haas Executive Director of the Morris Arboretum, received the prestigious Liberty Hyde Bailey Award from the American Horticultural Society (AHS) at its June 5th Great American Gardeners Awards Ceremony at River Farm in Alexandria, Virginia.
The human body is comprised of roughly 10 times more bacterial cells than human cells. In healthy people, these bacteria are typically harmless and often helpful, keeping disease-causing microbes at bay. But, when disturbances knock these bacterial populations out of balance, illnesses can arise. Periodontitis, a severe form of gum disease, is one example.
Costs for a lifetime of support for each individual with autism spectrum disorder may reach $2.4 million, according to a new study from researchers from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia.