Shitian Wei, MCS ‘20

Bachelor of Science in Chemistry, Nanjing University—Jiangsu, China
Future plans: Pursue a career in industry

Capstone: Understanding the role of three specific amino acid residues on capsid assembly and interaction with core protein allosteric modulators (CpAMs)

Hepatitis B virus (HBV) chronically infects more than 250 million people worldwide and causes 680, 000 deaths annually due to liver failure and hepatocellular carcinoma (HCC). This project intended to establish an in vivo capsid assembly assay, to further understand the mechanism of HBV capsid assembly through interaction between CpAMs and Cp dimer.

Download Shitian’s capstone poster >