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Research in the Dmochowski lab encompasses
many
areas of Bioinorganic, Bioorganic, and Biophysical Chemistry, as well as Chemical Biology. Our lab
is comprised of people with backgrounds spanning these disciplines. We are
developing
small molecules, proteins, and spectroscopic techniques for
studying complex biomolecular systems. Our approach involves cycles of molecular design, synthesis, and measurement.
 We are synthesizing light-activated oligonucleotides and Xe-129
MRI contrast agents to elucidate
protein interactions involved in vertebrate development,
limb regeneration, and the progression of many diseases, including
cancer. We are also developing novel nano/biomaterials using
proteins for the synthesis and assembly of
metal nanoparticles.
Useful Links Ivan@UPenn Chemistry UPenn Department of Chemistry American Chemical Society |
Recent Highlights
2007 September XinJing's work to turn genes off with light using caged PNAs appears as JACS comm. August Aru, Joe, and XinJing present results at Boston ACS meeting. Aru's work measuring xenon binding to cryptophane in water appears as JACS comm. July Lei's paper studying gold nanoparticles with apoferritin is accepted for the Ed Stiefel Issue of J. Inorg. Biochem. April Ivan is named a Camille and Henry Dreyfus Teacher-Scholar. |