Dmochowski Group


Research in the Dmochowski lab encompasses many areas of Bioinorganic, Bioorganic, and Biophysical Chemistry, as well as Chemical Biology. Our lab is comprised of people with backgrounds spanning these disciplines. We are developing small molecules, proteins, and spectroscopic techniques for studying complex biomolecular systems. Our approach involves cycles of molecular design, synthesis, and measurement.


Group News

  • Congratulations to Brittani and Sean for their recent J. Inorg. Biochem. review of caged oligonucleotides for studying biological systems. DOI: 10.1016/j.jinorgbio.2015.03.010
  • Congratulations to Yanfei for her recent ChemComm paper on using cucurbit[6]uril as an ultrasensitive Xe-129 NMR contrast agent. DOI: 10.1039/C5CC01826A
  • Congratulations to Brittany and Yanfei for their recent JACS paper on "Smart" Xe NMR biosensors for pH-dependent cell labeling. DOI: 10.1021/jacs.5b01938
  • Congratulations to Julie and Teresa for their recent Chemical Science paper on ruthenium-caged antisense morpholinos for regulating gene expression. DOI: 10.1039/c4sc03990d)
  • Julie successfully completes her Ph.D. thesis! Congratulations Julie!
  • Teresa presents "Catch and release: Using visible light-activated ruthenium polypyridyl compounds to cage oligonucleotides" at the 248th ACS National Conference in San Francisco.
  • Yubin and Yanfei's paper "Bacterial spore detection and analysis using hyperpolarized 129Xe chemical exchange saturation transfer (Hyper-CEST) NMR" published in Chemical Science. (DOI: 10.1039/C4SC01190B)
  • Yanfei and Teresa win TA awards. Congratulations!
  • Olena, Yubin, and Ed's paper  "Enantiopure cryptophane-129Xe nuclear magnetic resonance biosensors targeting carbonic anhydrase" published in Supramolecular Chemistry. (DOI: 10.1080/10610278.2014.906601)
  • Yubin successfully completes his Ph.D. thesis! Congratulations Yubin!
  • Brittani, Sean, and Julie's paper "Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue" published in Nature Methods. (DOI: 10.1038/nmeth.2804)