Research in the Dmochowski lab
encompasses many areas of Bioinorganic, Bioorganic, and
Biophysical Chemistry, as well as Chemical Biology. Our lab is
comprised of people with backgrounds spanning these disciplines.
We are developing small molecules, proteins, and spectroscopic
techniques for studying complex biomolecular systems. Our approach
involves cycles of molecular design, synthesis, and measurement.
to Brittani and Sean for their recent J. Inorg.
Biochem. review of caged oligonucleotides for
studying biological systems. DOI:
to Yanfei for her recent ChemComm paper on
using cucurbituril as an ultrasensitive Xe-129 NMR
contrast agent. DOI:
to Brittany and Yanfei for their recent JACS
paper on "Smart" Xe NMR biosensors for pH-dependent
cell labeling. DOI:
- Congratulations to Julie and Teresa for
their recent Chemical
Science paper on ruthenium-caged antisense
morpholinos for regulating gene expression. DOI:
- Julie successfully completes her Ph.D. thesis!
- Teresa presents "Catch and release: Using
visible light-activated ruthenium polypyridyl
compounds to cage oligonucleotides" at the 248th ACS
National Conference in San Francisco.
- Yubin and Yanfei's paper "Bacterial spore
detection and analysis using hyperpolarized 129Xe
chemical exchange saturation transfer (Hyper-CEST)
NMR" published in Chemical
- Yanfei and Teresa win TA awards.
- Olena, Yubin, and Ed's paper "Enantiopure
cryptophane-129Xe nuclear magnetic
resonance biosensors targeting carbonic anhydrase"
published in Supramolecular
- Yubin successfully completes his Ph.D. thesis!
- Brittani, Sean, and Julie's paper
"Transcriptome in vivo analysis (TIVA) of spatially
defined single cells in live tissue" published in Nature
Methods. (DOI: 10.1038/nmeth.2804)