Welcome to the Kozlowski Group Homepage
Special congratulations to Alison, Erin, and Ariel on selection of our paper on chemically reversible mechanochromic sensor as a JACS spotlight! link
Welcome to Nossir and Kailash, who will be doing research in the group this fall. Kailash's Profile
MCK is organizing the 2015 National Organic Symposium. Check out the awesome speaker line-up at: NOS 2015
Congratulations to Scott and Osvaldo on publication with the Bode group of a direct displacement mechanism for carbonyl substitution in the highly utilized active ester for peptide synthesis. link
Congratulations to Erin and Alison on publication in JACS of the chemically reversible mechanochromic bisphenazines link
Congratulations to Rosaura Padilla-Salinas and Carilyn Torruellas on completion of their Ph.D. degrees! We send them off with good wishes for the future.
Welcome to undergraduates Prosper Dzanwa (Moorehouse College), Kyle Niederer (College of Scranton), Harry Glicklich (Penn) and Luke Chen (Penn) to the group for the summer.
Kudos to Young and crew on publication of the selective phenol cross-coupling in JACS.
Welcome new graduate students Sergei Tcyrulnikov and Erin Nigro.
MCK has been elected a Fellow of the American Chemical Society, see announcement.
Welcome to Melinda Wang, John Todaro, and David Jungreis, Penn undergradautes, who will be working in the lab this summer
Kudos to Ro, Ryan, and Scott on publication of their massive review of Aerobic Copper-Catalyzed Chemistry in Chemical Reviews !
Welcome to Ariel Klinghoffer and Kaila Orlandini, two high school students working on projects in the group
Congratulations to the boss Prof. Kozlowski for becoming the newest Associate Editor for Journal of Organic Chemsitry (JOC) ! See official announcement at the JOC website!
Congratulations to the Penn Merck HTE Lab expansion! See link for news article!
Congratulations to Scott Allen on successfully defending his thesis. We wish him luck as he moves on as a postdoc with Albert Bowers at UNC, Chapel Hill.
Due to a recently funded NIH instrumentation grant, the Penn-Merck High Throughput Experimentation Laboratory has undergone a significant expansion adding a UPLC-MS, a mass directed automated HPLC, and a Symyx Robot Platform. Thanks to everyone for their efforts in making these major additions come together.
Many congratulations to Trung Cao and Erin Podlesny who successfully defended their PhD dissertations this month. We wish them the best as they go off to their postdocs with Jeff Bode at ETH Zürich and Tim Jamison at MIT, respectively.
Congratulations to MCK for recognition as a Fellow of the American Association for the Advancement of Science.
Welcome to Osvaldo Gutierrez, a new postdoc joining us from Dean Tantillo's group at U.C. Davis.
Congratulations to Phuong Huynh and Ryan Walvoord on the publication of the communication: 'Rapid Quantification of the Activating Effects of Hydrogen Bonding Catalysts with a Colorimetric Sensor', which was just accepted to JACS! DOI
Congratulations to Erin Podlesny on the publication of her article! DOI
Congratulations to former group member Dr. Michael Fennie who is starting an academic position at the University of Scranton after spending several successful years at Sanofi-Aventis.link
Prof. Kozlowski has been selected to receive the2012 American Chemical Society Award. The award lecture will be Thursday, October 18 at the University of Pennsylvania.
We are all excited for Ro, who will be getting married next weekend. We wish her many years of happiness!
We bid summer students Kim Mullane and Sergei Tcyrulnikov farewell. Kim will be starting in the Ph.D. chemistry program at Penn and Sergei is headed back to St. Petersburg State University in Russia to complete his M.S. in chemistry. Good luck Kim and Sergei!
Congratulations to Rosaura Padilla-Salinas, Erin Podlesny, John Curto, Ryan Walvoord, Carilyn Torruellas, Scott Allen, and Alison Metz, who all did a fantastic job with their talks and posters at the ACS National Meeting here in Philadelphia.
Welcome to Brad Hutnick, a new postdoc joining us from Scott Nelson's group at the University of Pittsburgh.
Congratulations to the former group members of the perylenequinone total synthesis team: Dr. Carol Mulrooney, Dr. Erin O'Brien and Dr. Barbara Morgan. Their recent review on natural products in Eur. J. Org. Chem. was one of the top ten most accessed articles from the journal in July 2012! (DOI)
Congratulations to Ryan Walvoord and Dr. Simon Berritt on the publication their coupling of aryl halides with nitromethane in Org. Lett. (DOI) It is one of the "Top 10 Most Read Articles in July 2012" even though it only posted on July 27! There is a really fun post highlighting this work and nitromethane in James Bond movies at the Synthetic Remarks Blog. http://syntheticremarks.com/?p=2953
Congratulations to Scott Allen on publication of his article in JACS. Working together with out colleagues from ETH Zurich, Prof. Bode and Jess Mahatthananchai, he identifies the mechanism and key control elements in the N-heterocyclic carbene asymmetric hetero-Diels-Alder reaction, including a nifty CH-pi interaction between an alkene and an aryl group. (DOI)
June 2012: Congratulations to Erin Podlensy on her J. Nat. Prod. paper on the total synthesis of a chiral binaphthalenetetrol. (DOI ) It has been selected as a Synfacts highlight, and has been stimulated quite a bit of interest on scientific blogs such as In the Pipeline.
February 2012: The Kozlowski group welcomes Dr. Avital Steinberg as our new computational postdoc!
January 2012: Welcome to Kelsey Van Gelder, a first year chemistry PhD student who is joining the group.
October 2011: Congratulations to Erin Podlesny on completing the first total synthesis of (S)-5,5'-bisoranjidiol!
August 2011: Prof. Kozlowski has written an overview of the utility of copper in organic synthesis in the book Copper-Oxygen Chemistry.
March 2011: Congratulations to Trung Cao and his wife on the birth of their son, Kien, who was born on March 3, 2011!
January 2011:Welcome to Young Eun Lee, our newest graduate student, who officially joined the group this semester.
December 2010: The University of Pennsylvania, Merck, and NSF's GOALI Program are proud to present: the UPenn Merck Catalysis Center, one of three academic HTE (High Throughput Experimentation) facilities in the nation.
July 2010: Professor Kozlowski has been awarded the 2010 Philadelphia Organic Chemists Club award. The award symposium will be on October 28, 2010 and will feature talks from Scott Miller (Yale), Mary Mader (Lilly), Stephen Waters (Univ. of Vermont), and Marisa Kozlowski (Penn). See http://www.pocclub.org/ for more details.
June 2010: Congratulations to Trung Cao on the event of his marriage.
January 2010:Welcome to Alison Metz, Carilyn Torruellas, and Phuong Huynh, first year chemistry PhD students who are joining the group.
January 2010: Welcome to new postdoctoral fellow Simon Berritt who will begin work at Merck, Rahway on the GOALI collaboration in rapid reaction optimization.
December 2009: Kudos to the entire perylenequinone team on publication of five back-to-back papers in the Journal of Organic Chemistry. The cover page of the first issue of the Journal of Organic Chemistry in 2010 will illustrate our chemistry with a nifty picture of the helical chiral natural products and a background showing of cercosporin being produced by the natural mold. DOI DOI DOI DOI DOI
August 2009: We are very excited about funding of the NSF GOALI proposal in collaboration with Merck, Gary Molander, and Patrick Walsh focusing on rapid parallel screening for reaction development and optimization. This effort will include development of a the CReDO (Center for Reaction Development and Optimization) center at Penn with instrumentation for multi-well plate reactions and screening.July 2009: Congratulations to Joshua Dickstein on completing his Ph.D. at Penn! He now moves on to Bridgestone America in Ohio
July 2009: Much fun was had at the group picnic and reunion celebrating MCK's promotion to Full Professor including tasting of Joshua Dickstein's home-brewed beer. See pictures here.
July 2009: Congratualations to Barbara Morgan on completing her Ph.D. at Penn! She is looking forward to starting at the Broad Institute in Boston in August.
July 2009: Congratulations to Elizabeth Linton on completing her Ph.D. at Penn! She now moves on to teach at Mastery Charter School in Philadelphia.
March 2009: Synfacts has highlighted our Hypocrellin A synthesis. Congratulations to Erin O'Brien and Barbara Morgan: DOI
January 2009: Welcome to John Curto and Rosaura Padilla-Salinas, first year chemistry PhD students who are joining the group.
December 2008: Congratulations to Liz Linton on publication of her catalytic asymmetric Meerwein-Eschenmoser Claisen rearrangement in J. Am. Chem. Soc. which has also been highlighted in Synfacts DOI DOI
November 2008: Congratulations to Joshua Dickstein and Michael Fennie on publication of the three component alpha-iminoester couplings via an umpolung process in J. Am. Chem. Soc. DOI
September 2008: After much work, "Fundamentals of Asymmetric Catalysis" has been published!! Thanks to all of those who helped this day arrive. Buy your copy while it's hot! See http://www.uscibooks.com/
September 2008: Congratulations to Brian Hewgley on publication of his copper kinetics work, including the discovery of a small molecule catalyst that works like a self-processing enzyme, in JACS. DOI
August 2008: Congratulations to Barbara Jane, Liz, Joshua, and Andrew on your presentations at the 236th ACS Meeting in Philadelphia.
July 2008: Our Hypocrellin A synthesis has been highlighted in the Chemistry World "Totally Synthetic" Blog! http://www.rsc.org/chemistryworld/Issues/2008/July/ColumnTotallySynthetic.asp
May 2008: Congratulations to Barbara Jane Morgan on receipt of a SAS Dissertation Fellowship.
May 2008: Kudos to Erin O'Brien and Barbara Jane Morgan for the first total synthesis of Hypocrellin A which appears in Angewandte Chemie International Edition: DOI
January 2008: Welcome to the group to Dr. Sangeeta Dey from the University of Nebraska at Lincoln, Ph.D. with David Berkowitz.
January 2008: Welcome to Scott Allen, Erin Podlesney, Ryan Walvoord, and Trung Cao, first year Chemistry PhD students who are joining the group.
August 2007: Congratulations to Erin O'Brien on completing her Ph.D. at Penn! She now moves on the Roche Palo Alto.
July 2007: Our aromatic decarboxylation communication in Organic Letters (DOI) is one of the most accessed articles of the quarter. Congratulations Josh!