Joullié Group

University of Pennsylvania

Group Home Page

Madeleine M. Joullié

Current Group Members

Research

Recent Publications

News & Events

Group Alumni

Positions Available

Links

Contact Us

Recent Publications

Perrin, L.; André, F.; Aninat, C.; Picoux, R.; Mahy, J. P.; Shangguan, N.; Joullié, M. M. Intramoleuclar hydrogen bonding as a determinant of the inhibitory potency of N-unsubstituted imidazole derivatives towards mammalian hemoproteins. Metallomics, 2009, *.

Joullié, M. M.; Berritt, S.; Forbeck, E. M. Synthetic Studies of hetreocyclic natural products. Curr. Opin. Drug Disc. Develop. 2008, 11, 829-852.

Faler, C. A.; Joullié, M. M. Substituted azabicylco[3.1.0]hexan-1-ols from aspartic and glutamic acid derivatives via titanium-mediated cyclopropanation. 2008, 49, 6512-6513.

Wan, X.; Joullié, M. M. Enantioselective Syntheses of Trichodermamides A and B. J. Am. Chem. Soc. 2008, in press.

Shangguan, N.; Hehre, W. J.; Ohlinger, W. S.; Beavers, M. P.; Joullié, M. M.  The Total Synthesis of Roquefortine C and a Rationale for the Thermodynamic Stability of Isoroquefortine C over Roquefortine C. J. Am. Chem. Soc. 2008, 130, 6281-6287. DOI

Li, P.; Evans, C. D.; Wu, Y.; Cao, B.; Hamel, E.; Joullié, M. M.  Evolution of the Total Syntheses of Ustiloxin Natural Products and Their Analogues J. Am. Chem. Soc. 2008, 130, 2351-2364. DOI

Forbeck, E. M.; Evans, C. D.; Gilleran, J. A.; Li, P.; Joullié, M. M.  A Regio- and Stereoselective Approach to Quaternary Centers from Chiral Trisubstituted Aziridines.  J. Am. Chem. Soc. 2007, 129, 14463-14469. DOI

Adrio, J.; Cuevas, C.; Manzanares, I.; Joullié, M. M. Total Synthesis and Biological Evaluation of Tamandarin B Analogues. J. Org. Chem. 2007, 72, 5129-5138. DOI

Faler, C.; Joullié, M. M. The Kulinkovich Reaction in the Synthesis of Constrained N,N-Dialkyl Neurotransmitter Analogues. Org. Lett.  2007, 9, 1987-1990. DOI

Wan, X.; Doridot, G.; Joullié, Progress towards the Total Synthesis of Trichodermamides A and B: Construction of the Oxazine Ring Moiety. Org. Lett. 2007, 9,  977-980. DOI

Joullié, M. M. Outsourcing; Blessing or Curse? C & E News, September 25, 2006. DOI

Sarotti, A. M.; Joullié, M. M.; Spanevello, R. A.; Suarez, A. G. Microwave Assisted Regioselective Cycloaddition Reactions between 9-Substituted Anthracenes and Levoglucosenone. Org. Lett. 2006, 8, 5561-5564. DOI

Li, P.; Forbeck, E. M.; Evans, C. D.; Joullié, M. M. Trisubstituted Aziridine Ring Opening by Phenol Derivatives: Stereo and Regioslective Formation of Chiral Tertiary Alkyl-Aryl Ethers. Org. Lett. 2006, 8, 5105-5107. DOI

Li, P.; Evans, C. D.; Forbeck, E. M.; Park, H.; Bai, R.; Hamel, E.; Joullié, M. M. Total synthesis and biological evaluation of ustiloxin natural products and two analogs. Bioorg. Med. Chem. Lett. 2006, 16, 4804-4807. DOI

Faler, C. A.; Joullié, M. M.  Aminolysis of allyl esters with bislithium aryl amides.              Tetrahedron Lett. 2006, 47, 7229-7231. DOI

Adrio, J.; Cuevas, C.; Manzanares, I.; Joullié, M. M.  Synthesis and Biological Evaluation of Tamandarin B Analogues.  Org Lett., 2006, 8,  511-514. DOI

Faler, C. A.; Cao, B.; Joullié, M. M.  Synthesis of Bicyclic Cyclopropylamines from Amino Acid Derivatives.  Heterocycles, 2006, 68,  519-522.

Hansen, D. B.; Lewis, A. S.; Gavalas, S. J.; Joullié, M. M.  A Stereoselective Synthetic Approach to (2S,3R)-N-(1’,1’-dimethyl-2’,3’-epoxypropenyl)-3-hydroxytryptophan, a Component of Cyclomarin A.  Tetrahedron: Asymm. 2006, 17, 15-21.  DOI  

Hansen, D. B.;  Joullié, M. M.  A Stereoselective Synthesis of (2S,3R)-b-Methoxyphenylalanine: a component of cyclomarin A.  Tetrahedron: Asymm. 2005, 16.  3963-3969.  DOI 

Hansen, D. B.; Starr, M. L.; Tolstoy, N. ; Joullié, M. M.  A Stereoselective Synthesis of (2S, 4R)-delta-hydroxyleucine Methyl Ester: A Component of Cyclomarin A.  Tetrahedron- Asymm. 2005, 16,  3623-3627. DOI   

Li, P.; Evans, C. D.; Joullié, M. M.  A Convergent Total Synthesis of Ustiloxin D via an Unprecedented Copper-Catalyzed Ethynyl Aziridine Ring Opening by Phenol Derivatives.  Org. Lett. 2005, 7,  5325-5327. DOI      

Hansen, D. B.; Wan, X.; Carroll, P. J.; Joullié, M. M.  Stereoselective Synthesis of Four Stereoisomers of Beta-methoxytyrosine, a Component of Callipeltin A.  J. Org. Chem.  2005, 70,  3120-3126. DOI

Hansen, D. B.; Joullié, M. M. The Development of Novel Ninhydrin Analogues. Chem. Soc. Rev.2005, 34. 408-417. DOI