Presently, the Saven
group uses primarily theory and computation to study biomolecules,
polymers, and condensed phase systems. Most of the research involves
of statistical mechanics to liquids and macromolecules.
thrust of the group involves computational protein design
and developing computational tools for understanding the properties
of protein sequences consistent with a chosen three-dimensional
structure. The group works closely with experimental
groups at Penn
and at other universities; some group members are involved in
joint theoretical/experimental projects.
Recent projects involve
the design of soluble and membrane bound proteins, discerning the
origins of conservation in naturally occurring proteins, biomolecular
simulation, design of nonbiological folding molecules, and developing
physically-based search methods for sequence databases.
can learn more about my research interests at my Chemistry Department page.