Theodore Schurr

Professor of Anthropology; Acting Graduate Group Chair
Phone:
215-573-7632
Email:

University Museum, Room 432

Website

Bio

I am a Professor in the Department of Anthropology, and a ConsultingCurator in the Physical Anthropology and American Sections of the University ofPennsylvania Museum of Archeology and Anthropology.  I am also the Director of the North AmericanRegional Center of the Genographic Project, and Head of the Laboratory ofMolecular Anthropology at the University of Pennsylvania.

Forthe past twenty-five years, I have investigated the genetic prehistory of Asiaand the Americas through studies of mtDNA, Y-chromosome and autosomal DNA variationin Asian, Siberian and Native American populations.  Our current projects include studies ofgenetic diversity in indigenous populations of Canada, the United States,Mexico and the Caribbean.  My researchgroup is also investigating the population history of Georgia (Caucasus), Pakistanand Kazakhstan through our collaborative genetic studies in those countries.

 

Courses Taught:

ANTH104 Sex and Human Nature

ANTH106 Anthropological Genetics

ANTH244 Disease and Human Evolution

ANTH246/649 Molecular Anthropology

ANTH249 Evolutionary Medicine

ANTH602 Evolutionary Anthropology

ANTH695 Current Topics in Molecular Anthropology

Education

M.A. Emory University, 1996; Ph.D. Emory University 1998

Office Hours

By appointment

Research Interests

Subject areas: Human evolutionary genetics, mitochondrial biology and disease, biomedical genetics, ancient DNA, primate genetics; Geographic areas: Africa, Americas, Australia, Georgia (Caucasus), Melanesia, Siberia, South Asia, Southeast Asia, Turkey

Selected Publications

PUBLISHED SINCE 2010:

Books and Edited Volumes:

Weber AW, Katzenberg MA, Schurr TG, eds. 2010. Prehistoric Hunter-Gatherers of the Baikal Region, Siberia: Bioarchaeological Studies of Past Lifeways. Philadelphia: University of Pennsylvania Press.

Peer-Reviewed Articles:

Nagle N, Ballantyne KN, van Oven M, Tyler-Smith C, Xue Y, Wilcox S, Wilcox L, Turkalov R, van Oorschot RAH, van HolstPellekaan S, Schurr TG, McAllisterP, Williams L, Kayser, Mitchell RJ, The Genographic Consortium. 2016. Mitochondrial DNA diversity of present-day Aboriginal Australians and implications for human evolution inOceania. J Hum Genet advanceonline publication, 1 December 2016; doi:10.1038/jhg.2016.147.

JotaMS, Lacerda DR, Sandoval JR, Vieira PPR, SoaresDOQ, Santos-Júnior JE, Acosta O, Cuellar C, Revollo S, Paz-y-Miño C, Fujita R,Vallejo GA, Schurr TG,Tarazona-Santos EM, Peña SDJ, Ayub Q, Tyler-Smith C, Santos FR, TheGenographic Consortium. 2016. New native South American Y-chromosome lineages. J Hum Genet DOI: 10.1038/jhg.2016.26.

Krzywanski DM, Moellering DR, Westbrook DG, Dunham-Snary KJ, Brown J, Bray AW, Feeley KP, SammyMJ, Smith MR, Schurr TG, Vita JA, AmbalavananN, Calhoun D, Dell’Italia L, Ballinger SW. 2016. Endothelialcell bioenergetics and mitochondrial DNA damage differ in humans having Africanor West Eurasian maternal ancestry. Circ Cardiovasc Genet DOI: 10.1161/CIRCGENETICS.115.001308.

Schurr TG, Yardumian Y, Shengelia R, Bitadze L, Chitanava D, Laliashvili S, Laliashvili I, Sanders A, Azzam A, Groner V, Edleson K, Vilar M. 2015. Genetic diversity and population history in Svaneti, northwestern Georgia. Caucasiologic Papers 7: 319-336.

Benn Torres J, Vilar MG, Torres G, GaieskiJB, Bharath Hernandez R, Browne ZE, Stevenson M, WatersW, Schurr TG, The Genographic Consortium. 2015. Genetic diversity in Carib and Garifunapopulations of the Lesser Antilles reveals significant indigenous ancestry andinsights into Caribbean settlement history. PLoSONE 10(10): e0139192 doi:10.1371/journal.pone.0139192.

Babb PL, Fernandez-DuqueE, Schurr TG. 2015. Monogamous owlmonkeys differ in the structure of OXTRfrom other non-monogamous primates. MolPhylogenet Evol 91: 160–177.

Badano I, Totaro ME, Culasso ACA, Sanabria DJ, Schurr TG, Balette IC, Roisman A, Basiletti J, Picconi MA, CamposRH, Domingo LJ. 2015. Genetic characterization and clinical implications of humanpapillomavirus type 16 (HPV16) variants from northeastern Argentina. Infect Genet Evol 29:103-105.

Vilar MG, Melendez C, Sanders A, Walia A, Gaieski JB, Owings AC, Schurr TG, The Genographic Consortium. 2014. Geneticdiversity in Puerto Rico and its implications for the peopling of the WestIndies. Am J Phys Anthropol 155:352–368.

HuckM, Fernandez-Duque E, Babb PL, Schurr TG. 2014. Correlates of genetic monogamy in pair-living mammals: Insights from Azara’sowl monkeys. Proc Roy Soc Lond B 281(1782): 20140195.

Elhaik E, Tatarinova T, Chebotarev D, Piras IS,Calò CM, De Montis A, Atzori M, Marini M, Tofanelli S,Francalacci P, Pagani L, Tyler-Smith C, Yali Xue Y, Cucca F, SchurrTG, Gaieski JB, MelendezC, Vilar MG, Owings AC, Gomez R, Fujita R, Santos FR, Comas D,Balanovsky O, Balanovska E, Zalloua P, Soodyall H, Pitchappan R, GaneshPrasadA, Hammer M, Matisoo-Smith L, Wells RS, The Genographic Consortium. 2014. Geographic population structure (GPS) of worldwide human populationsinfers biogeographical origin down to home village. Nat Commun 5: 3513doi:10.1038/ncomms4513.

Dingley S,Polyak E, Ostrovsky J, Srinivasan S, Lee I, Rosenfeld A, Tsukikawa, Xiao R, SelakM, Coon JJ, Hebert A, Grimsurd P, Pagliarini D, Gai X, Schurr TG, Hüttemann M, Ogiso-Nakamaru E, Falk MJ. 2014. MitochondrialDNA variant in COX1 subunit significantly alters energy metabolism ofgeographically divergent wild isolates in Caenorhabditiselegans. J Mol Biol 426(11):2199-2216.

Elhaik E, Greenspan E,Staats S, Krahn T, Tyler-Smith C, Xue Y, Tofanelli S, Francalacci P, Cucca F,Pagani P, Jin L, Li H, Schurr TG,Greenspan B, Spencer Wells RS, Genographic Consortium. 2013. The GenoChip: A new toolfor genetic anthropology. Genome Biol Evol 5:1021-1031.

Babb P,McIntosh AM, Fernandez-Duque E, SchurrTG. 2013. Prolactin receptor gene diversity in owl monkeys (Aotus spp.) and humans suggests anon-neutral evolutionary history among primates. InternatlJ Primatol 35:129–155.

FettermanJL, Zelickson BR, Johnson LW, Moellering DR, Westbrook DG, Pompilius M, SammyMJ, Salman ED, Johnson M, Dunham-Snary KJ, Cao X, Bradley WE, Zhang J, Wei CC,Chacko B, SchurrTG, Kesterson RA, Dell’Italia LJ, Darley-Usmar VM, Welch DR,Ballinger SW. 2013. Mitochondrial genetic background modulates bioenergeticsand susceptibility to acute cardiac volume overload. BiochemicalJournal 455:157–167.

Schurr TG, Dulik MC,Cafaro TA, Urrets-Zavalia EA, Urrets-Zavalia JA, Serra HM. 2013. Geneticbackground and climatic droplet keratopathy in a Mapuche population fromArgentina. PLoS ONE 8(9): e74593.

Badano I, SchurrTG, Stietz SM, Dulik MC, Mampaey M, Quintero IM, Zinovich JB,Campos RH, Liotta DJ. 2013. TNF promoter SNP variation in Amerindians andwhite-admixed populations from Misiones, Argentina. InternatlJ Immunogenet 40:216–221.

Dulik MC, Zhadanov SI, Osipova LP, Askapuli A,Gau L, Gokcumen O, Rubinstein S, Schurr TG. 2012. Mitochondrial DNA and Y-chromosome variation provides evidence for arecent common ancestry between Native Americans and Indigenous Altaians. Am J Hum Genet 90:1–18.

Badano I, Stietz S, Schurr TG, Picconi A, Fekete D, Quintero I, Cabrera M, Campos R, Liotta J. 2012. Analysis of TNF-a promoter SNPs and the risk of cervical cancer in urban populations of Posadas (Misiones, Argentina). J Clin Virol 53:54-59.

Xie HM, Perin JC, Schurr TG, Dulik MC, Zhadanov SI, Baur J, King M, Place E, Clarke C, Grauer M, Schug J, Santani A, Albano A, Kim C, Hakonarson H, Gai X, Falk MJ. 2011. Mitochondrial genome sequence analysis: A custom bioinformatics pipeline substantially improves Affymetrix MitoChip call rate and accuracy. BMC Bioinformatics 12:402.

Babb PL, McIntosh AM, Fernandez-Duque E, Di Fiore T, Schurr TG. 2011. An optimized genetic fingerprinting strategy reveals individual identity and kinship in Azara’s owl monkeys (Aotus azarai azarai). Folia Primatologia 82:107-117.

Gaieski JB, Owings AC, Vilar MG, Dulik MC, Gaieski D, Gittelman RM, Dulik MC, Lindo J, Gau L, Schurr TG, The Genographic Consortium. 2011. Genetic ancestry and indigenous heritage in a Native American descendant community in Bermuda. Am J Phys Anthropol 46(3): 392–405.

Yardumian A, Schurr TG. 2011. Who are the Anatolian Turks? A reappraisal of the anthropological genetic evidence. Archeol Anthropol Eurasia 50(1): 6-43 (Summer).

Babb PL, Fernandez-Duque E, Baiduc C, Gagneux P, Evan S, Schurr TG. 2011. Mitochondrial DNA diversity in Azara's owl monkey (Aotus azarai) of the Argentinean Chaco. Am J Phys Anthropol 146: 209-224.

Balanovsky O, Dibirova K, Dybo A, Mudrak O, Frolova S, Pocheshkhova E, Haber M, Platt D, Schurr TG, Haak W, Kuznetsova M, Radzhabov M, Balaganskaya O, Druzhinina E, Zakharova T, Koshel S, Renfrew C, Wells RS, Tyler-Smith C, Balanovska E, The Genographic Consortium. 2011. Parallel evolution of genes and languages in the Caucasus. Mol Biol Evol 28(10): 2905-2920.

Dulik MC, Osipova LP, Schurr TG. 2011. Y-chromosome variation in Altaian Kazakhs reveals a common paternal gene pool for Kazakhs and the influence of Mongol expansions. PLoS ONE 6(3): e17548.

Gokcumen O, Gultekin T, Dogan Alakoc Y, Tug A, Gulec E, Schurr TG. 2011. Biological ancestries, kinship connections, and projected identities in four central Anatolian settlements. Amer Anthropol 113(1): 116-131.

Book Chapters:

SchurrTG, Benn Torres J, Vilar MG,Gaieski JB, Melendez C. 2016. An emerging history of indigenous Caribbean and circum-Caribbean populations:Insights from archeological, ethnographic, genetic and historical studies. In:Zuckerman M, Martin DL, editors. New Directions in Biological Anthropology:Papers Honoring the Legacy of George Armelagos.Gainesville: University of Florida Press, pp.385-402.

SchurrTG. 2015. Where tides of genes perpetual ebb and flow: What DNA evidence tells usabout the peopling of the Americas. In: Suarez R, editor. The Early Human Occupation during the Ice Agein the Americas: New Directions andAdvances. Salt Lake City: University of Utah Press (inpress). 

SchurrTG. 2015. Tracing humanmovements from Siberia to the Americas: New insights from genetic studies. In: FrachettiMB, Spengler RN, III, editors. Mobilityand Ancient Society in Asia and the Americas. Basel: Springer,pp. 23-47. 

Schurr TG. 2014. Human genetic diversity in a globalcontext.In: Spooner BL, editor. Globalization: The Crucial Phase,Philadelphia: University of Pennsylvania Press, pp. 71-114.

Schurr TG. 2014. Thegenetic legacy of Genghis Khan. In: Fitzhugh W, Rossabi M, Honeychurch W,editors. GenghisKhan and the Mongol Empire, Washington DC:Arctic Studies Center and Odyssey Books, pp. 275-277.

Schurr TG. 2013. When did we become human? Evolutionaryperspectives on the emergence of the modern human brain and culture. In:Hatfield G, Pittman H, editors, TheEvolution of Mind, Brain and Culture. Philadelphia: University of Pennsylvania Museum Press, pp. 45-90.

Dulik MC, Lorenz JG, Schurr TG. 2011. Hasanlu IVB: An ancient DNA pilot project. In: Dyson R, M de Schaudensee, editors, Aspects of Peoples and Crafts in Period IVB at Hasanlu, Iran: Hasanlu Special Studies Volume 4, Philadelphia: University of Pennsylvania Museum Press, pp. 195-199.

Schurr TG, Pipes L. 2011. The prehistory of Mongolian populations: Evidence from cranio-facial, dental trait and genetic studies. In: Sabloff P, editor, Mapping Mongolia: Situating Mongolia in the World from Geologic Time to the Present, Philadelphia: University of Pennsylvania Museum Press, pp. 134-165.

Please contact me by email (tgschurr@sas.upenn.edu) to request a copy of any of these publications.

Affiliations

Anthropology Department Faculty; Department of Biology Graduate Group, University of Pennsylvania;Associate Member, Center for East Asian Studies, University of Pennsylvania;Member, CHOP Mitochondrial Research Affinity Group, School of Medicine, University of Pennsylvania;Research Associate, Population Studies Center, University of Pennsylvania;Member, International Center for Clinical Genetics, Kharkiv, Ukraine;Consortium Faculty, Penn Genomic Frontiers Institute;Consulting Curator, American and Physical Anthropology Sections, Penn Museum;Consortium Faculty, African Studies Center, University of Pennsylvania

Interests

Subfield

Faculty Status