Isabel was born in Monterrey, México where she resided until she moved to Mexico City to pursue her bachelors in Latinamerican Literature at the Universidad Iberoamericana. During this time she worked as a freelance style corrector for several magazines, an experience that came in handy during her time as Book Review Editor for the Hispanic Review. She has collaborated at Revista de Literatura Mexicana Contemporánea, the cultural magazine Letras Libres and the newspaper El País for "Viajeros Urbanos."
Her dissertation revolves around the intersections between the concept of the Mexican intellectual and contemporary notions of gender, nation, race, and class.
During her time at UPenn, Isabel has taught several language courses.