Sarah Tishkoff and Collaborators Receive Grant to Study How Genetic Ancestry Influences Health

Sarah Tishkoff, David and Lyn Silfen University Professor

An international team led by Sarah Tishkoff, David and Lyn Silfen University Professor in biology and genetics, has been awarded $2.7 million from the Chan Zuckerberg Initiative’s Donor Advised Fund. It is one of 16 new projects funded by the initiative to provide insights into how genetic ancestry influences health and disease at the level of our cells. Tishkoff and collaborators will study gene expression and epigenetic variation in African immigrant populations in Philadelphia, Detroit, and Belgium, as well as populations from Morocco and Tanzania. This project provides a unique opportunity to distinguish how genetics and environment impact gene expression and immune response in each of these populations, increasing the understanding of variable risk for multiple diseases.

Tishkoff holds appointments in Penn Arts & Sciences and Perelman School of Medicine, and is Director of Penn’s Center for Global Genomics and Health Equity. Her research combines field work, laboratory research, and computational methods to examine African population history and how genetic variation can affect a wide range of traits: for example, why humans have different susceptibility to disease, how they metabolize drugs, and how they adapt through evolution.

The Chan Zuckerberg Initiative works to help solve some of society’s toughest challenges, from eradicating disease and improving education to addressing the needs of local communities.

To read more about the project, click here.


Arts & Sciences News

Jolyon Thomas Appointed to Japan-U.S. Friendship Commission

Thomas researches religion in Japan and the U.S.

View Article >
Anthea Butler Receives 2022 Marty Award from the American Academy of Religion

The Geraldine R. Segal Professor of American Social Thought has received the 2022 Martin E. Marty Award for the Public Understanding of Religion.

View Article >
Recent Paper Co-Authored by Joseph Francisco Highlighted in Nature Communications

The Editors’ Highlights page showcases the 50 best papers recently published by the journal in specific areas of science.

View Article >
American Chemical Society Establishes New Award Honoring Marsha Lester

The award honors her exemplary scholarly accomplishments and leadership in the discipline.

View Article >
School of Arts & Sciences New Standing Faculty

Penn Arts & Sciences appointed 13 new faculty members for the 2022-23 academic year.

View Article >
Karen Goldberg Awarded Nichols Medal

The Vagelos Professor of Energy Research is recognized for her pioneering work in organometallic reaction mechanisms.

View Article >